|
Professor of Neurology B.S.
in Pharmacy (1966) Ph.D.
in Medicinal Chemistry (1970) Postdoctoral
training (1970-1973) |
| The primary interests of our laboratory are in the biology of neurotrophic factors and the molecular mechanisms of neuronal programmed cell death. We also are studying the physiology and pharmacology of novel neurotrophic factors which we isolated and cloned in collaboration with the lab of Dr. Jeffrey Millbrandt in the Dept. of Pathology. In order to pursue these interests a variety of cellular, morphological, biochemical and genetic methods are utilized. Our long range goal is to contribute to the amelioration of neuronal degenerative processes. |
| Pepose JS, Johnson EM Jr (2005 Jun). Is there a role for neurotrophin treatment of the ocular surface following laser in situ keratomileusis (LASIK)? Am J Ophthalmol. 139 (6): 1090-4. |
| Wei L, Cui L, Snider BJ, Rivkin M, Yu SS, Lee CS, Adams LD, Gottlieb DI, Johnson EM Jr, Yu SP, Choi DW (2005 Jun-Jul). Transplantation of embryonic stem cells overexpressing Bcl-2 promotes functional recovery after transient cerebral ischemia. Neurobiol Dis. 19 (1-2): 183-93. |
| Leitner ML, Wang LH, Osborne PA, Golden JP, Milbrandt J, Johnson EM Jr (2005 Feb). Expression and function of GDNF family ligands and receptors in the carotid body. Exp Neurol. 191 Suppl 1: S68-79. |
| Lee CS, Tee LY, Dusenbery S, Takata T, Golden JP, Pierchala BA, Gottlieb DI, Johnson EM Jr, Choi DW, Snider BJ (2005 Jan). Neurotrophin and GDNF family ligands promote survival and alter excitotoxic vulnerability of neurons derived from murine embryonic stem cells. Exp Neurol. 191 (1): 65-76. |
| Wang LH, Paden AJ, Johnson EM Jr (2005 Mar). Mixed-lineage kinase inhibitors require the activation of Trk receptors to maintain long-term neuronal trophism and survival. J Pharmacol Exp Ther. 312 (3): 1007-19. |
| Enomoto H, Hughes I, Golden J, Baloh RH, Yonemura S, Heuckeroth RO, Johnson EM Jr, Milbrandt J (2004 Nov 18). GFRalpha1 expression in cells lacking RET is dispensable for organogenesis and nerve regeneration. Neuron. 44 (4): 623-36. |
